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Development of Ion Mobility Spectrometry with Novel Atmospheric Electron Emission Ionization for Field Detection of Gaseous and Blister Chemical Warfare Agents

TitleDevelopment of Ion Mobility Spectrometry with Novel Atmospheric Electron Emission Ionization for Field Detection of Gaseous and Blister Chemical Warfare Agents
Publication TypeJournal Article
Year of Publication2019
AuthorsSeto Y., Hashimoto R., Taniguchi T., Ohrui Y., Nagoya T., Iwamatsu T., Komaru S., Usui D., Morimoto S., Sakamoto Y., Ishizaki A., Nishide T., Inoue Y., Sugiyama H., Nakano N.
JournalAnal Chem
Volume91
Issue8
Pagination5403-5414
Date PublishedApr 16
ISBN Number0003-2700 (Linking)
Accession Number30920801
Abstract

Drift tube ion mobility spectrometry with a novel atmospheric electron emission (AEE) source was developed for determination of gaseous and blister chemical warfare agents (CWAs) in negative mode. The AEE source was fabricated from an aluminum substrate electrode covered with 1 mum silver nanoparticle-dispersed silicone resin and a thin gold layer. This structure enabled stable tunneling electron emission upon the application of more than 11 V potential under atmospheric pressure. The reactant ion peak (RIP) was observed for the reduced mobility constant ( K0) of 2.18 and optimized at the charging voltage of 20 V. This RIP was assigned to O2(-) by using a mass spectrometer. Hydrogen cyanide was detected as a peak ( K0 = 2.47) that was discriminatively separated from the RIP (resolution = 1.4), with a limit of detection (LOD) of 0.057 mg/m(3), and assigned to CN(-) and OCN(-). Phosgene was detected as a peak ( K0 = 2.36; resolution = 1.2; and LOD = 0.6 mg/m(3)), which was assigned to Cl(-). Lewisite 1 was detected as two peaks ( K0 = 1.68 and 1.34; LOD = 12 and 15 mg/m(3)). The K0 = 1.68 peak was ascribed to a mixture of adducts of molecules or the product of hydrolysis with oxygen or chloride. Cyanogen chloride, chlorine, and sulfur mustard were also well detected. The detection performance with the AEE source was compared with those under corona discharge and (63)Ni ionizations. The advantage of the AEE source is the simple RIP pattern (only O2(-)), and the characteristic marker ions contribute to the discriminative CWAs detection.

URLhttps://www.ncbi.nlm.nih.gov/pubmed/30920801
DOI10.1021/acs.analchem.9b00672
Short TitleDevelopment of Ion Mobility Spectrometry with Novel Atmospheric Electron Emission Ionization for Field Detection of Gaseous and Blister Chemical Warfare Agents

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