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Sulfur Mustard Library

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Phenidone and hydroxyurea reduce sulfur mustard-increased proteolysis in hairless guinea pig skin, Cowan, F. M., Bongiovanni R., Broomfield C. A., Schulz S. M., and Smith W. J. , J Toxicol Cutaneous Ocul Toxicol, Volume 14, p.265-272, (1995) Abstract
Sulfur mustard exposure enhances Fc receptor expression on human epidermal keratinocytes in cell culture: implications for toxicity and medical countermeasures, Cowan, F. M., Broomfield C. A., and Smith W. J. , J Cell Biol Toxicol, Aug, Volume 14, Issue 4, p.261-266, (1998) Abstract
Sulfur mustard-increased proteolysis following in vitro and in vivo exposures, Cowan, F. M., Yourick J. J., and Hurst C. G. , Proceedings of the U.S. Army Medical Defense Bioscience Review, May 10-13, Volume 1, Baltimore, MD, p.49-55, (1993)
Enhanced proteolytic activity and Fc receptor expression in human epithelial cels following exposure to sulfur mustard, Cowan, F. M., Broomfield C. A., and Smith W. J. , Proceedings of the U.S. Army Medical Defense Bioscience Review, (1996)
Sulfur mustard- and phosgene-increased IL-8 in human small airway cell cultures: Implications for medical countermeasures against inhalation toxicity, Cowan, F. M., Smith W. J., Moran T. S., Paris M. M., Williams A. B., and Sciuto A. M. , Pentagon Reports, Aberdeen Proving Ground, MD, p.8, (2005) Abstract
Effect of sulfur mustard exposure on protease activity in human peripheral blood lymphocytes, Cowan, F. M., Broomfield C. A., and Smith W. J. , Proceedings of the NATO, Panel VIII Meeting, Grenoble, France, (1991)
A review of multi-threat medical countermeasures against chemical warfare and terrorism, Cowan, F. M., Broomfield C. A., Stojilijkovic M. P., and Smith W. J. , Mil Med, Volume 169, p.850-855, (2004) Abstract
Inhibition of sulfur mustard-increased protease activity by niacinamide, N-acetyl-I-cysteine, or dexamethasone, Cowan, F. M., Broomfield C. A., and Smith W. J. , Proceedings of the U.S. Army Medical Defense Bioscience Review, (1991)
Suppression of sulfur mustard-increased IL-8 in human keratinocyte cell cultures by the COX inhibitor indomethacin, the poly (ADP-ribose) polymerase (PARP) inhibitor 3-(4' bromophenyl) ureidobenzamide and the calmodulin antagonist fluphenazine, Cowan, F. M., Broomfield C. A., and Smith W. J. , Proceedings of the U.S. Army Medical Defense Bioscience Review, Hunt Valley, MD, (2002)
Sulfur mustard-increased proteolysis following in vitro and in vivo exposures, Cowan, F. M., Yourick J. J., Hurst C. G., Broomfield C. A., and Smith W. J. , Pentagon Reports, Aberdeen Proving Ground, MD, p.8, (1993) Abstract
Putative roles of inflammation in the dermatopathology of sulfur mustard, Cowan, F. M., and Broomfield C. A. , Cell Biol Toxicol, Jul-Sep, Volume 9, Issue 3, p.201-213, (1993)
Exposure of human epidermal keratinocyte cell cultures to sulfur mustard promotes binding of complement C1q: implications for toxicity and medical countermeasures, Cowan, F. M., Broomfield C. A., and Smith W. J. , J Appl Toxicol, Dec, Volume 20 Suppl 1, p.S77-80, (2000) Abstract
Sulfur mustard-increased proteolysis following in vitro and in vivo exposures, Cowan, F. M., Yourick J. J., Hurst C. G., Broomfield C. A., and Smith W. J. , Proceedings of the 31st Annual Meeting of the Society of Toxicology, Volume 12, Seattle, WA, p.362, (1992) Abstract
Sulfur mustard-increased elastase-like activity in homogenates of hairless guinea pig skin, Cowan, F. M., Bongiovanni R., Broomfield C. A., Yourick J. J., and Smith W. J. , J Toxicol Cutaneous Ocul Toxicol, Volume 13, p.221-229, (1994)
Sulfur mustard increased proteolysis in cultured human cells, Cowan, F. M., Broomfield C. A., and Smith W. J. , Advances in Alternatives for Safety and Efficacy Testing, Volume Chapter 28, p.277-283, (1998)
Sulfur mustard-increased proteolysis following in vitro and in vivo exposures, Cowan, F. M., Yourick J. J., Hurst C. G., Bongiovanni R., Broomfield C. A., and Smith W. J. , Proc of the 20th Army Science Conference, Volume 2, p.705-709, (1996)
Biochemical alterations in rat lung lavage fluid following acute sulfur mustard inhalation. II. Increases in proteolytic activity, Cowan, F. M., Anderson D., Broomfield C. A., Byers S. L., and Smith W. J. , Inhalation Toxicol., Volume 9, p.53-61, (1997) Abstract
Increased proteolytic activity in human epithelial cells following exposure to sulfur mustard, Cowan, F. M., Broomfield C. A., and Smith W. J. , Proc of the NATO Panel 8 - RSG III Meeting, Salisbury, England, (1995)
Sulfur mustard- and phosgene- increased IL-8 in human small airway cell cultures: Implications for medical countermeasures against inhalation toxicity, Cowan, F. M., Smith W. J., Moran T. S., Parris M. M., Williams A. B., and Sciuto A. M. , Proceedings of the U.S. Army Medical Defense Bioscience Review, Aberdeen Proving Ground, MD, (2004) Abstract
Increased proteolytic activity in human epithelial cells following exposure to sulfur mustard, Cowan, F. M., Broomfield C. A., and Smith W. J. , Proc of the U.S. Army ERDEC Scientific Conference on Chemical and Biological Defense Research, (1995)
Sulfur mustard- and phosgene-increased IL-8 in human small airway cell cultures, Cowan, F. M., Smith W. J., Moran T. S., Paris M., Williams A. D., and Sciuto A. , Pentagon Reports, Aberdeen Proving Ground, MD, p.9, (2004) Abstract
Inhibition of sulfur mustard-increased protease activity by niacinamide, N-acetyl-I-cysteine, or desamethasone, Cowan, F. M., Broomfield C. A., and Smith W. J. , FASEB J, Volume 5, p.A828, (1991)
Suppression of sulfur mustard-increased IL-8 in human keratinocyte cell cultures by serine protease inhibitors: Implications for toxicity and medical countermeasures, Cowan, F. M., Broomfield C. A., and Smith W. J. , Alternative Toxicological Methods for the New Millennium, Volume Chapter 28, Boca Raton, FL, p.313-321, (2003)
Sulfur mustard increased proteolysis following in vitro and in vivo exposures, Cowan, F. M., Yourick J. J., Hurst C. G., Broomfield C. A., and Smith W. J. , Proc of the USA-Israel Bilateral Medical Research & Development Symposium: The "Shoresh" Conference, (1994)
Putative role of proteolysis and inflammatory response in the toxicity of nerve and blister chemical warfare agents: implications for multi-threat medical countermeasures, Cowan, F. M., Broomfield C. A., Lenz D. E., and Smith W. J. , J Appl Toxicol, May-Jun, Volume 23, Issue 3, p.177-186, (2003) Abstract
Suppression of sulfur mustard-increased IL-8 in human keratinocyte cell cultures by serine protease inhibitors: implications for toxicity and medical countermeasures, Cowan, F. M., Broomfield C. A., and Smith W. J. , Cell Biol Toxicol, Volume 18, Issue 3, p.175-180, (2002) Abstract
Sulfur Mustard-Increased Proteolysis Following In Vitro and In Vivo Exposures, Cowan, F. M., Yourick J. J., Hurst C. G., Broomfield C. A., and Smith W. J. , Proceedings of the 1993 Medical Defense Bioscience Review, Baltimore, MD, p.49-55, (1993)
Putative role of proteolysis and inflammatory response in the toxicity of nerve and blister chemical warfare agents: implications for multi-threat medical countermeasures, Cowan, F. M., Broomfield C. A., Lenz D. E., and Smith W. J. , J.Appl.Toxicol., 05, Volume 23, Issue 3, p.177-186, (2003) Abstract
Exposure of human epidermal keratinocyte cell cultures to sulfur mustard promotes binding of complement C1q: Implications for toxicity and medical countermeasures, Cowan, F. M., Broomfield C. A., and Smith W. J. , Proceedings of the U.S. Army Medical Defense Bioscience Review, Baltimore, MD, (1998)
Sulfur mustard increased proteolysis following in vitro and in vivo exposures, Cowan, F. M., Yourick J. J., Hurst C. G., Broomfield C. A., and Smith W. J. , The Toxicologist, Volume 12, p.112, (1992)
Sulfur mustard-increased proteolysis in hairless guinea pig skin is inhibited by phenidone and hydroxyurea, Cowan, F. M., Bongiovanni R., Broomfield C. A., Schulz S. M., and Smith W. J. , Proc of the NATO Panel 8 - RSG III Meeting, Munich, (1994)
Sulfur mustard exposure enhances Fc receptor expression in human epidermal keratinocytes in cell culture: Implications for toxicity and medical countermeasures, Cowan, F. M., Broomfield C. A., and Smith W. J. , U.S.Army Medical Research Institute of Chemical Defense, Issue 1, p.12, (1997)
Sulfur mustard and phosgene increased IL-8 in human small airway cell cultures: Implications for medical countermeasures against inhalation toxicity, Cowan, F. M., Smith W. J., Moran T. S., Parris M. M., Williams A. B., and Sciuto A. M. , Proceedings of the U.S. Army Medical Defense Bioscience Review, Hunt Valley, MD, (2004)
Inhibition of sulfur mustard-increased protease activity by niacinamide, N-acetyl-L-cysteine or dexamethasone, Cowan, F. M., Broomfield C. A., and Smith W. J. , Cell Biol Toxicol, Apr-Jun, Volume 8, Issue 2, p.129-138, (1992) Abstract
Sulfur mustard- and phosgene-increased IL-8 in human small airway lung cell cultures: Implications for medical countermeasures against inhalation toxicity, Cowan, F. M., Smith W. J., Moran T., Parris M. M., Williams A. B., and Sciuto A. M. , Proc. of the 2003 Joint Service Scientific Conference on Chemical & Biological Defense Research, Towson, MD, (2003)
Effect of sulfur exposure on protease activity in human peripheral blood lymphocytes, Cowan, F. M., Broomfield C. A., and Smith W. J. , Cell Biol Toxicol, Jul, Volume 7, Issue 3, p.239-248, (1991) Abstract
Suppression of sulfur mustard-increased IL-8 and TNF in human keratinocyte cell cultures by a novel anti-inflammatory drug: Implications for multi-threat medical countermeasure (MTMC) against nerve and blister agents, Cowan, F. M., Lefkowitz C. A., Broomfield C. A., Burstein S. H., and Smith W. J. , Proceedings of the U.S. Army Medical Defense Bioscience Review, Hunt Valley, MD, (2002)
Sulfur mustard increased proteolysis following in vitro and in vivo exposures, Cowan, F. M., Yourick J. J., Hurst C. G., Broomfield C. A., and Smith W. J. , Proc of the Symposium - "Alkylating Agents", Centre d'Etudes du Bouchet, France, (1995)
Anti-inflammatory and morphocytotoxic actions of 4-methyl-2-mercaptopyridine-1-oxide in sulfur mustard-exposed skin and lung epithelial cell cultures: Implications for broad spectrum countermeasures, Cowan, F. M., Broomfield C. A., Nealley E. W., and Petrali J. P. , Proceedings of the U.S. Army Medical Defense Bioscience Review, Hunt Valley, MD, p.88, (2006) Abstract
Suppression of sulfur mustard-increased IL-8 in human keratinocyte cell cultures by serine protease inhibitors: Implications for toxicity and medical countermeasures, Cowan, F. M., Broomfield C. A., and Smith W. J. , Proceedings of the U.S. Army Medical Defense Bioscience Review, Baltimore, MD, (2000)
Sulfur mustard-increased proteolysis following in vitro and in vivo exposures, Cowan, F. M., Yourick J. J., Hurst C. G., Broomfield C. A., and Smith W. J. , Cell Biol Toxicol, Jul-Sep, Volume 9, Issue 3, p.269-277, (1993) Abstract
Putative role of proteolysis in the inflammatory and neurological toxicity of nerve and blister chemical warfare agents, Cowan, F. M., Broomfield C. A., Lenz D. E., Shih T. - M., and Smith W. J. , Proceedings of the U.S. Army Medical Defense Bioscience Review, Baltimore, MD, (2000)
Enhanced proteolytic activity and Fc receptor expression in human epithelial cells following exposure to sulfur mustard, Cowan, F. M., Broomfield C. A., and Smith W. J. , Toxicity Assessment Alternatives: Methods, Issues, Opportunities, Volume Chapter 16, p.185-191, (1999)
Sulfur mustard-increased proteolysis following in vitro and in vivo exposures, Cowan, F. M., Yourick J. J., Hurst C. G., Broomfield C. A., and Smith W. J. , Proceedings of the U.S. Scientific Conference on Chemical Defense Research, Edgewood, MD, (1992)
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Doxycycline and HBED iron chelator decrease IL-8 production by sulfur mustard exposed human keratinocytes, Nicholson, J. D., Cowan F. M., Bergeron R. J., Brimfield A. A., Baskin S. I., and Smith W. J. , Proceedings of the U.S. Army Medical Defense Bioscience Review, Volume 224, Aberdeen Proving Ground, MD, p.1-11, (2004) Abstract
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Increased proteolytic activity in human epithelial cells following exposure to sulfur mustard, Smith, W. J., Cowan F. M., and Broomfield C. A. , FASEB J, Volume 5, p.A828, (1991)
Biochemical changes induced in human cells by the vesicating agent sulfur mustard, Smith, W. J., Clark O. E., Cowan F. M., DeJoseph M. E., and Gross C. L. , Proceedings of the U.S. Army Medical Defense Bioscience Review, Baltimore, MD, (2000)
Human epidermal keratinocytes exposed in vitro to the vesicating agent sulfur mustard express markers of apoptosis and inflammation, Smith, W. J., Neally E. W., Clark O. E., and Cowan F. M. , Proc of the NATO TG004 Panel, Oslo, Norway, (2002)
The use of human cells in culture to study the mechanism of action and therapeutic approaches to cutaneous injury by sulfur mustard, Smith, W. J., Martens M. E., Gross C. L., Clark O. E., and Cowan F. M. , Proc. of the Congress on Cell and Tissue Culture, San Diego, CA, (1993)
Therapeutic approaches to cutaneous injury by sulfur mustard, Smith, W. J., Martens M. E., Gross C., Clark O. E., and Cowan F. M. , Proc of the 1996 US/Israeli Bilateral Scientific Data Exchange (Shoresh Conference), (1996)
Biochemical and flow cytometric studies of the mechanism of action of sulfur mustard using human cells in culture, Smith, W. J., Martens M. E., Gross C., Clark O. E., and Cowan F. M. , Proc of the USA-Israel Bilateral Medical Research & Development Symposium; The "Shoresh" Conference, (1994)
Increased proteolytic activity in human epithelial cells following exposure to sulfur mustard, Smith, W. J., Cowan F. M., and Broomfield C. A. , Proceedings of the U.S. Army Medical Defense Bioscience Review, (1991)
Biochemical changes induced in human cells by the vesicating agent sulfur mustard, Smith, W. J., Clark O. E., Cowan F. M., DeJoseph M. E., and Gross C. L. , In Vitro, Volume 36, p.79A, (2000)
Human epidermal keratinocytes exposed in vitro to the vesicating agent sulfur mustard express markers of apoptosis and inflammation, Smith, W. J., Nealley E., Clark O. E., and Cowan F. M. , Proceedings of the U.S. Army Medical Defense Bioscience Review, Hunt Valley, MD, (2002)
Studies of cellular biochemical changes induced in human cells by sulfur mustard, Smith, W. J., Clark O. E., Cowan F. M., DeJoseph M. E., Davenport C., and Gross C. , Proc of the USA-Israel Bilateral Medical Research & Development Symposium: The "Shoresh" Conference, (1999)
The use of human cells in culture to study the mechanism of action and therapeutic approaches to cutaneous injury by sulfur mustard, Smith, W. J., Martens M. E., Gross C. L., Clark O. E., and Cowan F. M. , Proc. of the World Congress on Alternatives and Animal Use in Life Sciences, Baltimore, MD, (1993)
Therapeutic approaches to cutaneous injury by sulfur mustard, Smith, W. J., Martens M. E., Gross C., Clark O. E., and Cowan F. M. , Proc of the 20th Army Science Conference, Volume 2, p.699-703, (1996)
The use of human cells in culture to study the mechanism of action and therapeutic approaches to cutaneous injury by sulfur mustard, Smith, W. J., Martens M. E., Gross C., Clark O. E., and Cowan F. M. , Proc of the NATO Panel 8 - PSG III Meeting, Munich, (1994)
A review of multi-threat medical countermeasures against chemical warfare and terrorism, Smith, W. J., Cowan F. M., Broomfield C. A., and Stojiljkovic M. P. , Pentagon Reports, Aberdeen Proving Ground, MD, p.7, (2004) Abstract
Studies of cellular biochemical changes induced in human cells by sulfur mustard, Smith, W. J., Clark O. E., Cowan F. M., De-Joseph M. E., and Gross C. L. , Alternative Toxicological Methods for the New Millennium, Volume Chapter 22, Boca Raton, FL, p.259-267, (2003)
Studies of cellular biochemical changes induced in human cells by sulfur mustard, Smith, W. J., Clark O. E., Cowan F. M., DeJoseph M. E., Davenport C., and Gross C. , Proc of the NATO TG-004 Meeting, Brussels, (1999)
Human epidermal keratinocytes exposed in vitro to the vesicating agent sulfur mustard express markers of apoptosis and inflammation, Smith, W. J., Nealley E., Clark O. E., and Cowan F. M. , In Vitro, Volume 37(3), p.47A, (2001)
The use of in vitro systems to define therapeutic approaches to cutaneous injury by sulfur mustard, Smith, W. J., Martens M. E., Gross C., Clark O. E., and Cowan F. M. , Toxicity Assessment Alternatives: Methods, Issues, Opportunities, Volume Chapter 19, p.205-212, (1999)
Therapeutic approaches to cutaneous injury by sulfur mustard, Smith, W. J., Martens M. E., Gross C., Clark O. E., and Cowan F. M. , Proc of the Symposium - "Alkylating Agents", Centre d'Etudes du Bouchet, France, (1995)
Biochemical events in the pathology of sulfur mustard in vitro, Smith, W. J., Cowan F. M., Clark C. R., Martens M. E., and Gross C. , Proceedings of the U.S. Army Medical Defense Bioscience Review, (1991)